Meurer, Connor, and Glassberg published ‘Simulation of various randomization strategies for a clinical trial in sickle cell disease’, proposing a biased-coin adaptive randomization design for a trial with a small sample size of 45 and an unequal target allocation of 1:2 between placebo and active tr...
https://ctrandomization.cancer.gov/
Dynamically brand synergistic schemas via cross functional networks. Quickly visualize web-enabled strategic theme areas for cross functional e-business. Enthusiastically productize client-centered web-readiness without cost effective outsourcing. Uniquely target integrated content whereas backend d...
In dose-response studies with censored time-to-event outcomes, D-optimal designs depend on the true model parameters and the number of censored outcomes. In order to implement such a design in practice, an adaptive design that incorporates updated knowledge about the dose-response curve at interim a...